Table 3.
Mutants under negative selection in the presence of a sub-inhibitory concentration of CTX in vitro that are impaired for systemic colonization of BALB/c mice.
| gene number | gene symbol | function |
|---|---|---|
| STM3524 | glpG | protein of glp regulon |
| STM0183 | folK | 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, PPPK |
| STM2141 | fbaB | 3-oxoacyl-[acyl-carrier-protein] synthase I (fructose-bisphosphate aldolase) |
| STM2385 | yfcB | putative methylase |
| STM3119 | putative monoamine oxidase | |
| STM3534 | glgP | glycogen phosphorylase |
| STM2076 | hisA | N-(5′-phospho-L-ribosyl-formimino)-5-amino-1-(5′-phosphoribosyl)-4-imidazolecarboxamide isomerase |
| STM14_0085 | caiB | l-carnitine dehydratase |
| STM0549 | fimZ | fimbrial protein Z |
| STM3733 | pyrE | orotate phosphoribosyltransferase |
| STM1496 | putative dimethylsulfoxide reductase | |
| STM1190 | yceD | putative metal-binding |
| STM3609 | yhjE | putative MFS family transport protein |
| STM0419 | thiL | thiamin-monophosphate kinase |
| STM4010 | putative hydrolase | |
| STM3377 | putative nitrate reductase | |
| STM1793 | putative cytochrome oxidase, subunit II | |
| STM1626 | trg | methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor |
| STM1187 | rluC | 23S rRNA pseudouridylate synthase |
| STM0765 | putative cation transporter | |
| STM3833 | putative mandelate racemase/muconate lactonizing enzyme family | |
| STM0565 | putative periplasmic protein | |
| STM1931 | araH | putative intracellular protease/amidase |