Figure 5.

(Top panels) Hyperthermia predictions for variable tumour size (open circle, marker) when c_ref is fixed to 1 mg ml⁻¹. The trend of the injected concentration of particles required to maintain c_ref constant is shown on the right. Error bars visualize the temperature heterogeneity, namely the difference $\underset{\mathit{\Omega }}{max}\mathrm{\Delta }T-\underset{\mathit{\Omega }}{min}\mathrm{\Delta }T$, when the tumour size increases. (Bottom panels) Calculated IONP concentration and temperature maps at time 40 min for tumour size of 8 mm (δ=16).