variables that alter as the simulations progress |
y |
vertical coordinate of the solution profile |
z |
horizontal coordinate of the solution profile |
|
vertical coordinate of the reference configuration |
|
horizontal coordinate of the reference configuration |
yc
|
vertical coordinate of the cortex |
zc
|
horizontal coordinate of the cortex |
θ |
solution profile normal angle measured anticlockwise from the z-axis |
s |
solution profile arc length |
σ |
reference configuration arc length |
κs
|
longitudinal principal curvature |
κϕ
|
azimuthal principal curvature |
λs
|
arc length stretch ratio |
Ts=yts
|
scaled form of the surface tension, ts, along the arc length |
tϕ
|
surface tension along the azimuthal coordinate |
Qs=yqs
|
scaled form of the normal shear stress, qs
|
parameters that are constant throughout a simulation |
ΔP
|
pressure difference across the membrane |
C |
concentration of adhesions |
F |
adhesion force |
E |
adhesion extension |
E0
|
adhesion resting length |
Ec
|
adhesion breaking length |
κ |
neo-Hookean spring constant |
α and β
|
intrinsic adhesion properties scaling the force–extension relationship |
η1
|
rate of cortex retraction |
η2
|
rate of membrane retraction |
ρ |
radius of the initial reference configuration sphere |
σ0
|
initial reference configuration arc length |
μ |
relative extensibility of the membrane in the azimuthal and longitudinal directions |