Table 3.
Correlation between selected tumor marker expression and infiltrating immune cells in HIV-related DLBCL.
| Stromal immune cells | CD4 | CD8 | FOXP3 | CD68 |
|---|---|---|---|---|
|
|
||||
| Selected tumor markers | Pearson’s Correlation Coefficienta (P-value) |
|||
| BCL2 | −0.01 (p=0.93) | 0.08 (p=0.52) | −0.08 (p=0.53) | −0.07 (p=0.57) |
| BCL6 | −0.17 (p=0.17) | −0.00 (p=0.98) | −0.31 (p=0.01) | −0.14 (p=0.26) |
| P53 | 0.25 (p=0.04) | −0.1 (p=0.40) | 0.37 (p<0.01) | 0.13 (p=0.30) |
| cMYC | 0.16 (p=0.18) | −0.01 (p=0.95) | 0.32 (p<0.01) | 0.01 (p=0.91) |
| Ki-67 | 0.04 (p=0.73) | 0.03 (p=0.83) | 0.09 (p=0.50) | −0.22 (p=0.07) |
Numbers in bold are correlations that are statistically significant at P-value <0.10 level.
a
Pearson’s correlation coefficient ranges from 0 to 1, with 0 being independent and 1 being perfect correlation. A negative value indicates an inverse association.