Table 1.

Association between HER2 status and clinicopathological parameters

	Overall	HER2 positive	HER2 negative	P value	HER2 (3+)	HER2 (2+)	HER2 (0, 1+)	P value
	n = 124 (%)	13(10.5)	111 (89.5)		13(10.5)	10 (8.1)	101(81.4)
Age at diagnosis				0.803				0.590
≥60 years	82 (66.1)	9	73		9	8	65
<60 years	42 (33.9)	4	38		4	2	36
Gender				0.865				0.459
Male	64 (51.6)	7	57		7	7	50
Female	60 (48.4)	6	54		6	3	51
Tumor topography				0.720				0.709
Distal stomach	100(80.6)	10	90		10	9	81
Proximal stomach/GEJ	24 (19.4)	3	21		3	1	20
Histological subtype				0.048				0.009
Intestinal	61 (49.2)	11	50		11	9	41
Diffuse	21 (16.9)	0	21		0	0	21
Mixed	33 (26.6)	2	31		2	1	30
Unditermined	9 (7.3)	0	9		0	0	9
Histological grade				0.004				<0.001
Well	13 (10.5)	4	9		4	1	8
Moderately	45 (36.3)	7	38		7	8	30
Poorly	66 (53.2)	2	64		2	1	63
Lymphovascular invasion				0.031				0.060
Positive	94 (75.8)	13	81		13	6	75
Negative	30 (24.2)	0	30		0	4	26
Blood-vessel invasion				0.395				0.170
Positive	44 (35.5)	6	38		6	1	37
Negative	80 (64.5)	7	73		7	9	64
pT status				0.271				0.165
pT1	17 (13.7)	0	17		0	1	16
pT2	32 (25.8)	3	29		3	2	27
pT3	69 (55.6)	10	59		10	5	54
pT4	6 (4.9)	0	6		0	2	4
pN status				0.453				0.762
pN0	39 (31.5)	2	37		2	4	33
pN1	46 (37.1)	7	39		7	4	35
pN2	24 (19.3)	3	21		3	1	20
pN3	15 (12.1)	1	14		1	1	13
pM status				0.548				0.705
pM0	121(97.6)	13	108		13	10	98
pM1	3 (2.4)	0	3		0	0	3

Bold numbers represent P values with statistical significance