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. 2015 Oct 13;16(10):24127–24138. doi: 10.3390/ijms161024127

Figure 4.

Figure 4

Kinetics of cytokine production following BCG-infected splenic DCs and MΦs. Splenic macrophages (A) and dendritic cells (B) were infected with BCG at a MOI of 5, and the cell culture supernatants were collected and detected at different time points after infection; Splenic macrophages (C) and dendritic cells (D) were infected with different MOIs of BCG, and the cell culture supernatants were collected and detected at 16 h after infection; IL-6 and IFN-γ production increased significantly in M.bovis BCG-infected MΦs (E) and DCs (F) when the effect of IL-10 was blocked by soluble IL-10R. Data depicted represent the mean values ± SEM. Statistical significance was determined by a Student’s t-test (* p < 0.05, ** p < 0.01).