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. 2015 Oct 20;16(10):24946–24964. doi: 10.3390/ijms161024946

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Extraction socket location and μCT analysis: (a) 3D CBCT (Cone Beam Computed Tomography) reconstructions and (b) the teeth used for reference; (c) Superimposition 3D CBCT and μCT models; (d) Highlighted borderline of the extraction socket in the μCT models (red: gAPN-treated group, orange: BMP2-treated group, blue: Bio-Oss group, green: blank group). Representative 3D reconstruction of the trabecular structure in the extraction socket: (e) Blank; (f) Bio-oss; (g) gAPN and (h) BMP2; and (i) Changes in trabecular bone parameters, including trabecular bone volume normalised by tissue volume (BV/TV), trabecular thickness (Tb.Th), trabecular number (Tb.N), and trabecular separation (Tb.Sp) are shown as means ± SD, with n = 4. * p < 0.05, as determined by one-way ANOVA.