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Inhibitory effect of humanized anti-TLR4 antibody Fab on cytokine expression in cell culture supernatant of LPS-stimulated mouse macrophages. (A–D) represent levels of TNF-α, IFN-β, IL-1, IL-6 in mouse macrophage culture supernatant determined by ELISA analysis. L: LPS; A: humanized anti-TLR4 antibody. Data are shown as mean ± SD (n = 3, * p < 0.05, ** p < 0.01 compare to LPS group).
