Table 1.
Bivariate analysis according to the presence of non-alcoholic steatohepatitis (NASH).
| Variable * | Total Sample | With NASH | Without NASH | p |
|---|---|---|---|---|
| Age (years) | 37.2 ± 10.6 (n = 183) | 37.6 ± 11.0 (n = 141) | 35.5 ± 9.0 (n = 42) | 0.208 |
| Female | 153 (80.1) (n = 191) | 113 (79) (n = 143) | 40 (83.3) (n = 48) | 0.661 |
| BMI (kg/m2) | 43.7 ± 5.2 (n = 191) | 43.5 ± 5.0 (n = 143) | 44.1 ± 5.7 (n = 48) | 0.535 |
| Ferritin (µ/L) | 119 (67–208) (n = 169) | 123 (75–239) (n = 128) | 97 (58.5–173) (n = 41) | 0.120 |
| Iron (µ/L) | 76.4 ± 25.2 (n = 163) | 75.8 ± 24.1 (n = 125) | 78.4 ± 29.1 (n = 38) | 0.587 |
| ** AST (U/L) | 24 (19–31) (n = 183) | 25 (20–34) (n = 139) | 21.5 (16.3–26.8) (n = 44) | 0.007 |
| ** ALT (U/L) | 29 (21–47.8) (n = 183) | 32 (23–51) (n = 139) | 25 (17–29.5) (n = 44) | <0.001 |
| ALT > 1.5 × U/L | 28 (15.2) (n = 183) | 28 (20.1) (n = 139) | 0 (0.0) (n = 44) | 0.002 |
| Glucose (mg/dL) | 103.7 ± 34.3 (n = 188) | 106.7 ± 37.7 (n = 142) | 94.5 ± 17.9 (n = 46) | 0.036 |
| Glucose ≥ 126 mg/dL | 24 (12.8) (n = 188) | 22 (15.5) (n = 142) | 2 (4.3) (n = 46) | 0.086 |
| Platelets (10³/mm3) | 278.5 ± 68.6 (n = 172) | 283.3 ± 64.8 (n = 131) | 269 ± 68.8 (n = 41) | 0.233 |
| Total cholesterol (mg/dL) | 193 ± 42 (n = 186) | 196.6 ± 42.8 (n = 138) | 182.9 ± 38.3 (n = 48) | 0.052 |
| LDL-C (mg/dL) | 116 ± 41 (n = 186) | 117.4 ± 41.1 (n = 138) | 112 ± 41.1 (n = 48) | 0.438 |
| HDL-C (mg/dL) | 48.9 ± 13.7 (n = 186) | 48.4 ± 13.5 (n = 138) | 50.2 ± 14.3 (n = 48) | 0.427 |
| TG (mg/dL) | 122 (91–193) (n = 186) | 134 (96–198) (n = 138) | 105 (72–135) (n = 48) | 0.004 |
| TG ≥ 150 mg/dL | 68 (36.3) (n = 186) | 58 (42.0) (n = 138) | 9 (18.8) (n = 48) | 0.007 |
* Variables described by mean ± standard deviation, median (percentiles 25–75) or n (%); ** Normal values for ALT: 14–42 U/L and for AST: 10–42 U/L; n = number of cases; NASH = nonalcoholic steatohepatitis; BMI = body mass index; AST = aspartate aminotransferase; ALT = alanine aminotransferase; LDL-C = low density lipoprotein; HDL-C = high density lipoprotein.