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. 2015 Oct 26;16(10):25678–25690. doi: 10.3390/ijms161025678

Figure 2.

Figure 2

In vivo models generated with critically sized defects in rat calvarias filled with α-TCP/CS material. (a) After four weeks, rats were administered interferon (IFN)-γ, and bone regeneration was compared with that occurring in no-drug-treated control rats and zoledronate (Zol)-injected rats; (b) Micro-computed tomography and bone-mineral density (BMD) images of rat calvarias defects. Scale bars = 10 mm (long bars) or 2 mm (short bars); (c) Post-operative bone volumes/tissue volumes (BV/TV) and BMDs were measured each week. The data shown represent the mean ± standard deviation (SD; n = 4). * p < 0.05, ** p < 0.01 (Tukey–Kramer method).