A phylogenetic tree of frizzled sequences. Ce, C. elegans; D, D. melanogaster; Hs, human; Hv, Hydra vulgaris; Sd, Suberites domuncula. The dendrogram was generated using the ClustalW alignment program in MacVector and is meant to show qualitative groupings of related frizzled genes. For more extensive and authoritative sequence analysis, see [3,4,6,10,53].