Table 2.
Baseline characteristics of CLL patients
| All Patients | BCL-XL < median | BCL-XL > median | P | ||||
|---|---|---|---|---|---|---|---|
| (n = 38) | (n = 38) | ||||||
| Number | Value (range) | Number | Value (range) | No. (%) | Value (range) | ||
| Age, median (range), years | 64 (38–90) | 64.5 (38–90) | 64 (48–87) | N.S. | |||
| Sex, male/female | 52/24 | 22/16 | 30/8 | 0.08 | |||
| Rai Stage | N = 76 | ||||||
| Early (Stage 0/I/II) | 59 | 36 | 23 | ||||
| Advanced (Stage III/IV) | 17 | 2 | 15 | ||||
| Zap70 positive | 18 of 44 | 11 of 24 | 7 of 20 | 0.937 | |||
| CD38 positive | 22 of 53 | 10 of 27 | 12 of 26 | 0.110 | |||
| FISH | |||||||
| 17p | 7 of 35 | 1 of 19 | 6 of 16 | 0.275 | |||
| 11q | 6 of 35 | 4 of 19 | 2 of 16 | 0.666 | |||
| 13q14 | 22 of 35 | 12 of 18 | 10 of 17 | 0.733 | |||
| Trisomy 12 | 6 of 35 | 2 of 17 | 4 of 16 | 0.398 | |||