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. 2015 Feb 13;6(6):695–703. doi: 10.1111/1759-7714.12239

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© 2015 The Authors. Thoracic Cancer published by China Lung Oncology Group and Wiley Publishing Asia Pty Ltd.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Identification of the lapatinib acquired drug resistance model rBT474. (a) Comparison of the cell number of BT474 and rBT474 under microscope after treatment with 5 μM lapatinib for 24 hours. (b) The result of flow cytometry detection of BT474 and rBT474. (c) The difference in apoptosis rate between BT474 and rBT474 (n = 3). Lap, lapatinib. , Lap(−); , Lap(+).

Inline graphic — Identification of the lapatinib acquired drug resistance model rBT474. (a) Comparison of the cell number of BT474 and rBT474 under microscope after treatment with 5 μM lapatinib for 24 hours. (b) The result of flow cytometry detection of BT474 and rBT474. (c) The difference in apoptosis rate between BT474 and rBT474 (n = 3). Lap, lapatinib. , Lap(−); , Lap(+).