Table 1.
Immunohistochemical staining for 14-3-3σ in different histological types of tissues
| Histological classification | Sample No. | 14-3-3 σ IRS (%) | P-value | |||
|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | |||
| Bronchial epithelia | 36 | 1 (2.8) | 7 (19.4) | 7 (19.4) | 31 (58.4) | P < 0.001† |
| Squamous metaplasia | 19 | 3 (15.8) | 5 (26.2) | 2 (10.5) | 9 (47.5) | |
| Dysplasia/carcinoma in situ | 18 | 5 (27.8) | 5 (27.8) | 3 (16.6) | 5 (27.8) | |
| Invasive cancer | 40 | 14 (35.0) | 8 (20.0) | 11 (27.5) | 7 (17.5) | |
†
Bronchial epithelia versus squamous metaplasia versus dysplasia/carcinoma in situ versus invasive cancer (P-value from Kruskal-Wallis test). IRS, immunoreactivity scoring.