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Distribution of UGT1A1 of patients treated with IP (n = 30)
| Genotype | Genotype | n (%) | |
|---|---|---|---|
| UGT1A1*28 (n) | UGT1A1*6 (n) | ||
| TA6/6 (20) | G/G (21) | Wild-type | 12 (40.0) |
| TA6/6 (20) | A/G (8) | Single mutation | 7 (23.4) |
| TA6/7 (7) | G/G (21) | Singe mutation | 6 (20.0) |
| TA6/7 (7) | A/G (8) | Double mutation | 1 (3.3) |
| TA7/7 (3) | G/G (21) | Double mutation | 3 (10.0) |
| TA6/6 (20) | A/A (1) | Double mutation | 1 (3.3) |
IP, irinotecan plus cisplatin; UGT1A1, uridine diphosphate glucuronosyltransferase.
