Table 2.
Basic response characteristics of the excitatory and inhibitory neurons in intact rats
| MSG | IMP | MSG + IMP | Saline | NaCl | |
|---|---|---|---|---|---|
| AM | |||||
| Excitatory | |||||
| Latency (min)c | 10.4 ± 1.6 | 9.9 ± 1.7 | 6.3 ± 1.4 | 12.8 ± 2.5 | 10.1 ± 1.4 |
| Duration (min)c | 9.7 ± 1.0 | 9.8 ± 1.4 | 12.9 ± 2.9 | 7.1 ± 1.0 | 10.8 ± 1.3 |
| Magnitude (spikes/sec) | 1.5 ± 0.8 | 0.7 ± 0.4 | 0.4 ± 0.2 | 0.8 ± 0.4 | 1.4 ± 0.4 |
| Inhibitory | |||||
| Latency (min) | 9.2 ± 1.9 | 14.2 ± 2.7 | 10.0 ± 4.3 | 13.0 ± 3.0 | 16.0 ± 2.3 |
| Duration (min) | 8.2 ± 1.5a | 5.5 ± 1.3 | 11.9 ± 3.7 | 14.2 ± 2.5 | 9.9 ± 1.8 |
| Magnitude (spikes/sec)c | −1.8 ± 1.0 | −1.5 ± 1.2 | −5.0 ± 2.6 | −3.0 ± 1.6 | −3.0 ± 1.1 |
| LH | |||||
| Excitatory | |||||
| Latency (min)c | 13.1 ± 2.8 | 10.4 ± 2.2 | 13.9 ± 5.0 | 11.5 ± 2.7 | 17.3 ± 3.1 |
| Duration (min)c | 8.1 ± 2.7 | 7.3 ± 1.3 | 4.4 ± 0.4 | 9.5 ± 1.7 | 6.7 ± 2.4 |
| Magnitude (spikes/sec) | 1.3 ± 0.9 | 1.6 ± 0.6 | 0.5 ± 0.3 | 0.5 ± 0.6 | 2.1 ± 1.0 |
| Inhibitory | |||||
| Latency (min) | 13.6 ± 3.6 | 11.9 ± 2.4 | 15.4 ± 2.0 | 8.5 ± 2.1 | 10.3 ± 4.4 |
| Duration (min) | 7.8 ± 2.0a | 13.0 ± 2.1 | 8.9 ± 1.7 | 18.4 ± 2.1 | 17.3 ± 4.1 |
| Magnitude (spikes/sec)c | −8.2 ± 4.4 | −8.0 ± 2.8 | −6.9 ± 2.4 | −10.9 ± 5.2 | −20.9 ± 11.2 |
Data are expressed as mean ± SEM.
a, b, c
the value is significantly different from saline (a) or NaCl (b) in the same brain region or same solution in the other brain region (c) (Tukey’s test, P < 0.05).
AM, amygdala; LH, lateral hypothalamus; Saline, physiological saline.