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Genome-wide relationship between GC content and the rate of crossing over in A. thaliana. (a) Silent DNA (GC3); (b) intron DNA (GCi). Each crossing-over bin contains approximately 10% of the genes of the dataset. See Materials and methods for details of the measurement of GC content and the rate of crossing over, in centimorgans per megabase (cM/MB). The results are the same if only genes with total intron size greater than 100 nucleotides (or with larger cutoff values) are included.
