Table 1.
Body weight, muscle weight and CSA of the soleus and plantaris muscles after 7-days hind limb unloading
| CT | HU | HU + IWB | HU + IWB + HS | |
|---|---|---|---|---|
| Body weight (g) | 408.9 ± 6.7 | 384.0 ± 9.2 | 379.3 ± 6.0* | 356.3 ± 7.7* |
| Muscle weight (mg) | ||||
| SOL | 168.2 ± 6.7 | 116.3 ± 3.1* | 121.1 ± 3.7* | 131.1 ± 2.4*† |
| PLA | 435.0 ± 11.1 | 353.0 ± 9.3* | 370.5 ± 7.2* | 367.7 ± 10.2* |
| Relative muscle weight (mg/kg) | ||||
| SOL | 410.7 ± 12.8 | 303.8 ± 9.3* | 318.9 ± 7.7* | 368.7 ± 7.4*†‡ |
| PLA | 1063.7 ± 20.3 | 920.0 ± 16.1* | 977.5 ± 17.5* | 1032.6 ± 22.0†‡ |
| CSA (μm2) | ||||
| SOL | 3977.3 ± 195.7 | 2282.2 ± 136.2* | 2274.3 ± 184.8* | 3338.9 ± 421.7†‡ |
| PLA | 3330.1 ± 261.9 | 2581.1 ± 82.0* | 2510.6 ± 92.1* | 2839.6 ± 187.9 |
n = 10 (n = 6 for CSA) per group. CSA, cross-sectional area; CT, control; HU, hindlimb unweighting; HU + IWB, intermittent weight-bearing during HU; HU + IWB + HS, intermittent weight-bearing with heat stress during HU.
*
P < 0.05 versus CT
†
P < 0.05 versus HU
‡
P < 0.05 versus HU + IWB.