Table 1.

MDA-9/Syntenin in cancer: observed clinical correlations.

Cancer	MDA-9 enhanced invasion?	Tumor grade	Survival correlation	Years	Ref.
Melanoma	Yes	↑ with ↑ MDA-9	Not reported	2004– 2013	[15,25,38,67,107]
Glioma/GBM	Yes	↑ with ↑ MDA-9	↓ with ↑ MDA-9	2012 – 2014	[50,57]
Breast	Yes	↑ with ↑ MDA-9	↓ with ↑ MDA-9	2002 – 2013	[51,58,59]
UCC	Yes	↑ with ↑ MDA-9	Not reported	2013	[49]
SCLC	Yes	↑ MDA-9 in advanced disease	Not reported	2014	[62]
Uveal melanoma	Yes	↑ MDA-9 in recurrent cases	↓ with ↑ MDA-9	2012	[60]
Gastric	Yes	Only compared to control tissue	Not reported	2002	[58]

↑: Positively correlates (tumor grade) or elevated (MDA-9 expression); ↓: Negatively correlates (survival); GBM: Glioblastoma; MDA-9: Melanoma differentiation-associated gene – 9; SCLC: Small cell lung cancer; UCC: Urothelial cell carcinoma.