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. 2015 Nov 4;10(11):e0139876. doi: 10.1371/journal.pone.0139876

Table 5. Annual Cost Thresholds for Entecavir and Tenofovir.

Population Cost-saving (WTP $0) Highly cost-effective (WTP $6,800) Cost-effective (WTP $20,400)
ETV TDF ETV TDF ETV TDF
Non-cirrhotic HBeAg-positive $522 $523 $1,008 $788 $1,173 $986
Non-cirrhotic HBeAg-negative $378 $381 $1,313 $866 $1,442 $1,051
Cirrhotic HBeAg-positive $899 $697 $1,027 $861 $1,284 $1,190
Cirrhotic HBeAg-negative $886 $738 $1,120 $746 $1,065 $762

ETV, entecavir; TDF, tenofovir; WTP, willingness to pay.

Threshold between $6,800–20,400 according to the WHO 1-3x GDP for China.