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. 2015 Nov 4;10(11):e0141861. doi: 10.1371/journal.pone.0141861

Table 5. Stratification analysis for sex between Clear and CHB in female patients.

Polymorphisms Allele Clear (n = 208) CHB (n = 85) Clear vs.CHB
P OR (95%CI)
rs11866328 TT 11 (0.05) 6 (0.07)
TG 67 (0.32) 27 (0.32) 0.911 1.166 (0.080–17.071) a
GG 130 (0.63) 52 (0.61) 0.334 0.441 (0.084–2.321) b
TG+GG 197 (0.95) 79 (0.93) 0.410 0.502 (0.097–2.590) c
T 89 (0.21) 39 (0.23)
G 327 (0.79) 131 (0.77) 0.468 0.807 (0.453–1.439) d
rs10845858 AA 27 (0.13) 15 (0.18)
AG 115 (0.55) 40 (0.47) 0.108 0.430 (0.153–1.204) a
GG 66 (0.32) 30 (0.35) 0.486 0.648 (0.191–2.195) b
AG+GG 181 (0.44) 70 (0.41) 0.115 0.477 (0.190–1.198) c
A 169 (0.41) 70 (0.41)
G 247 (0.59) 100 (0.59) 0.777 0.932 (0.573–1.516) d
rs1041236 TT 112 (0.54) 51 (0.60)
TC 90 (0.43) 28 (0.33) 0.409 0.639 (0.221–1.849) a
CC 6 (0.03) 6 (0.07) 0.047 0.099 (0.0010–0.968) b
TC+CC 96 (0.46) 34 (0.40) 0.978 0.987 (0.380–2.562) c
T 314 (0.75) 130 (0.76)
C 102 (0.25) 40 (0.24) 0.492 1.304 (0.613–2.770) d
rs2013562 CC 38 (0.18) 17 (0.2)
CT 101 (0.49) 49 (0.58) 0.363 1.594 (0.583–4.357) a
TT 69 (0.33) 19 (0.22) 0.991 0.990 (0.173–5.673) b
CT+TT 170 (0.82) 68 (0.4) 0.597 1.308 (0.483–3.544) c
C 177 (0.43) 83 (0.49)
T 239 (0.57) 87 (0.51) 0.421 0.819 (0.502–1.334) d
rs7861010 AA 20 (0.10) 1 (0.01)
AG 82 (0.39) 55 (0.65) 0.994 - a
GG 106 (0.51) 29 (0.34) 0.992 - b
AG+GG 188 (0.90) 84 (0.99) 0.994 - c
A 122 (0.29) 57 (0.34)
G 294 (0.71) 11 (0.66) 0.836 1.078 (0.530–2.192) d
rs12206945 GG 16 (0.08) 4 (0.05)
GA 83 (0.40) 54 (0.63) 0.382 2.185 (0.379–12.584) a
AA 109 (0.52) 27 (0.32) 0.620 1.624 (0.239–11.051) b
GA+AA 192 (0.92) 81 (0.95) 0.502 1.773 (0.334–9.418) c
G 115 (0.28) 62 (0.36)
A 301 (0.72) 108 (0.64) 0.349 0.773 (0.451–1.324) d
rs10485138 TT 8 (0.04) 3 (0.04)
TC 74 (0.36) 47 (0.55) 0.385 0.232 (0.009–6.243) a
CC 126 (0.60) 35 (0.41) 0.187 0.096 (0.003–3.110) b
TC+CC 200 (0.96) 82 (0.96) 0.239 0.161 (0.008–3.369) c
T 90 (0.22) 53 (0.31)
C 326 (0.78) 117 (0.69) 0.005 0.445 (0.253–0.784) d
rs6909880 GG 21 (0.10) 6 (0.07)
GT 81 (0.39) 39 (0.46) 0.804 1.177 (0.326–4.246) a
TT 106 (0.51) 40 (0.47) 0.636 0.720 (0.185–2.808) b
GT+TT 187 (0.90) 79 (0.93) 0.838 0.888 (0.286–2.755) c
G 123 (0.30) 51 (0.30)
T 293 (0.70) 119 (0.70) 0.220 0.728 (0.439–1.209) d

SNP: single nucleotide polymorphisms, Clear: spontaneously recovered individuals with history of HBV infection, CHB: chronic hepatitis B patients. P values, ORs and 95% CIs were calculated by multiple logistic regression adjusting for age; - means differences could not be detected.

a means additive model: the first genotype/the second genotype

bmeans additive model: the first genotype/the third genotype

cmeans recessive model: the first genotype/the second +the third genotype

dmeans allele model.