Table 2.

Classification of all HU-selected strains, according to gene annotation [46-48]

Functional group	Number
Gene expression
Transcription	16
RNA processing	15
Nuclear/cytoplasmic transport	5
Translation	8
Total	44
Vesicular trafficking
Protein secretion	5
Vacuolar trafficking	17
Vacuolar H+-ATPase	11
Total	33
DNA replication
DNA synthesis/repair	38
Chromosome dynamics	29
Total	67
Cell polarization	18
Cell metabolism
Cell growth	7
Mitochondria	24
Amino acid metabolism	8
Nucleotide metabolism	7
Phosphate metabolism	3
Lipid metabolism	6
Carbohydrate metabolism	6
Heavy-metal metabolism	2
Oxidative protection	3
Total	66
Unknown	67
Total	295

See Additional data file 11 for more detail.