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| Regulatory | Stimulatory | |
|---|---|---|
| Mean # High | 1.79 | 1.99 |
| Median # High | 2.00 | 2.00 |
| HR per +1 High (95% CI) | ||
| Discovery | 1.46 (1.28-1.66) | 0.78 (0.72-0.85) |
| Validation | 1.49 (1.16-1.84) | 0.82 (0.67-0.99) |
| Median PFS | ||
| 0 High | 54.9 (n= 18) | 11.2 (n=20) |
| 1 High | 27.7 (n= 63) | 10.7 (n=63) |
| 2 High | 18.2 (n=126) | 19.1 (n=79) |
| 3 High | 10.5 (n= 45) | 35.4 (n=80) |
| 4 High | 76.9 (n=10) | |
