Table 3. Summary of neuropsychological assessment.
| Pt; n = 30 | HC; n = 19 | P value | ||||
|---|---|---|---|---|---|---|
| Pre | Post | Pre (base line) | Post (1 week) | |||
| Attention | ||||||
| D-CAT1 | 29.2 ± 5.2 | 31.4 ± 5.1 | 29.5 ± 5.4 | 35.5 ± 5.8 | 0.001 * | |
| D-CAT2 | 45.5 ± 8.1 | 48.0 ± 6.3 | 52.4 ± 9.9 | 48.8 ± 7.9 | 0.024 | |
| D-CAT3 | 50.3 ± 11.0 | 53.3 ± 9.7 | 59.0 ± 14.6 | 61.6 ± 12.2 | 0.28 | |
| Processing speed | ||||||
| Stroop 1 | 56.4 ± 10.3 | 57.9 ± 9.9 | 58.3 ± 9.7 | 63.2 ± 9.1 | 0.01 | |
| Stroop 3 | 39.9 ± 7.5 | 42.0 ± 7.2 | 46.1 ± 7.9 | 42.8 ± 6.3 | 0.005 | |
| Digit symbol cording | 68.8 ± 18.1 | 74.5 ± 18.2 | 77.5 ± 12.3 | 87.3 ± 14.1 | 0.06 | |
| Memory | ||||||
| Immediate story recall | 20.9 ± 6.9 | 29.8 ± 7.2 | 24.2 ± 4.7 | 29.5 ± 5.1 | 0.033 | |
| Delayed story recall | 16.3 ± 6.7 | 26.3 ± 8.5 | 20.1 ± 5.3 | 27.4 ± 6.0 | 0.27 | |
| Executive function | ||||||
| Stroop 2 | 48.6 ± 9.3 | 50.8 ± 9.6 | 53.0 ± 9.1 | 53.8 ± 8.2 | 0.60 | |
| Stroop 4 | 33.8 ± 8.7 | 34.8 ± 9.8 | 40.0 ± 11.4 | 41.2 ± 10.3 | 0.27 | |
| Working memory | ||||||
| Digit span (backward) | 5.9 ± 2.1 | 6.3 ± 2.4 | 7.0 ± 1.6 | 7.7 ± 1.8 | 0.17 | |
| Quality of life | ||||||
| WHO-QOL 26 (average overall) | 6.2 ± 0.8 | 6.3 ± 1.4 | 7.2 ± 1.2 | 7.2 ± 1.6 | 0.84 | |
Values are expressed as means ± SD.
P values express the between-group significance after 1 week, and were derived from ANCOVA models.
*Significant at P <0.0045 using Bonferroni correction in cognitive tests.
Abbreviations: Pt, Patients; HC, healthy controls; Pre, before surgery or baseline; Post, after surgery or 1 week after baseline; D-CAT, digit cancellation task; WHO QOL, World Health Organization quality of life.