Table 3. Differentially methylated CpG islands in 4C blastocyst group.
| EDMA_ ID | Chromosomal location of the DMRs | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chr. No | Start of the fragment | End of the fragment | Log2FC | P. value | CpG-I | CpG-L | Genes containing DMRs | Genomic region of DMRs | |
| 23_10636 | 23 | 50703682 | 50704205 | 0.717 | 0.0000 | 523 | 597 | WRNIP1-1 | Exon |
| 14_00311 | 14 | 2021102 | 2022310 | 0.67 | 0.0023 | 1018 | 316 | GRINA-7 | Exon |
| 07_01370 | 7 | 4445833 | 4448462 | 0.65 | 0.0002 | 1279 | 618 | CRTC1-14,-15 | Exon |
| 29_08515 | 29 | 48125388 | 48126127 | 0.61 | 0.0038 | 624 | 217 | PPFIA1-14 | Exon |
| 22_06844 | 22 | 47721645 | 47722113 | 0.59 | 0.0045 | 468 | 239 | CACNA1D- | Exon |
| 24_05434 | 24 | 41196455 | 41196870 | 0.90 | 0.0001 | 161 | 212 | PTPRM-13 | Intron |
| 01_04641 | 1 | 65593765 | 65594620 | 0.78 | 0.0000 | 222 | 222 | GPR156-7 | Intron |
| 12_00244 | 12 | 5198652 | 5199215 | 0.75 | 0.0001 | 563 | 2923 | PCDH17-4 | Exon |
| 09_10794 | 9 | 103164941 | 103165323 | 0.71 | 0.0002 | 307 | 266 | RPS6KA2-20 | Intron |
| 17_10379 | 17 | 70755932 | 70756476 | 0.64 | 0.0005 | 217 | 217 | AP1B1-16 | Exon |
| 05_19144 | 5 | 121066466 | 121067409 | 0.63 | 0.0001 | 650 | 264 | MLC1-1 | Intron |
| 24_08819 | 24 | 58000202 | 58000701 | 0.62 | 0.0005 | 207 | 207 | NEDD4L-15 | Intron |
| 12_11235 | 12 | 90547550 | 90548313 | 0.61 | 0.0035 | 640 | 366 | PCID2-3 | Exon |
| 09_09020 | 9 | 96614497 | 96615244 | 0.60 | 0.0006 | 719 | 248 | EZR-8 | Exon |
| 26_08607 | 26 | 49756976 | 49757126 | 0.60 | 0.0013 | 78 | 234 | GLRX3-4 | Exon |
| 08_12515 | 8 | 102986219 | 102986674 | -0.64 | 0.0441 | 455 | 496 | UGCG | Ppromoter |
| 19_06047 | 19 | 28409208 | 28410192 | -0.67 | 0.0054 | 134 | 947 | VAMP2-2-4 | Exon |
| 18_16952 | 18 | 62701913 | 62702419 | -0.69 | 0.0275 | 506 | 1529 | SYT5-2 | Exon |
| 26_00146 | 26 | 4831864 | 4832162 | -0.69 | 0.0187 | 65 | 327 | PCDH1-1,-2 | Intron |
| 07_09727 | 7 | 45330243 | 45331467 | -0.82 | 0.0282 | 1188 | 1364 | MIDN-1 | Exon |
| 17_12362 | 17 | 74231699 | 74233071 | 0.72 | 0.0004 | 326 | 1318 | PI4KA-37 | Exon |
| 08_00160 | 8 | 880729 | 882384 | 0.67 | 0.0013 | 1258 | 1258 | PALLD-10 | Intron |
| 06_12635 | 6 | 118964269 | 118964779 | 0.63 | 0.0021 | 510 | 468 | AFAP1-6 | Intron |
| 18_02124 | 18 | 8100425 | 8100718 | 0.62 | 0.0007 | 106 | 323 | LOC782414-9 | Intron |
| 29_04592 | 29 | 36902489 | 36903114 | 0.60 | 0.0002 | 168 | 235 | APLP2-15 | Exon |
| 05_19063 | 5 | 120935146 | 120936857 | -0.61 | 0.0008 | 1711 | 6736 | CRELD2-4-5 | Exon |
CpG_L is the length of the island on the genome while CpG- I indicates the number of bases within the fragment which are part of the CpG Island. Numbers preceded by hyphen following the gene name in the “Genes containing DMRs” column indicate the exon or intron number depending whether the DMR is located in exon or intron of the gene. EDMA_ID refers to the identification ID of each EDMA probe. Each ID is preceded by EDMA_MET. PPromoter. = proximal promoter.