Skip to main content
. 2015 Nov 4;10(11):e0140467. doi: 10.1371/journal.pone.0140467

Table 4. Differentially methylated CpG islands in 16C blastocyst group.

EDMA_ID Chromosomal location of the DMRs
Chr. No Start of the fragment End of the fragment Log2 FC P. value CpG-I CpG-L Genes containing the DMRs Genomic region of DMRs
05_02664 5 26984478 26985074 0.95 0.0280 264 883 ZNF740-7 Exon
05_02793 5 27362031 27363304 0.70 0.0095 222 222 KERIA-1 Exon
14_04905 14 25007734 25008796 0.62 0.0147 1028 514 PLAG1-1 Exon
16_00691 16 2836340 2837002 0.74 0.0484 653 703 TMCC2-1 Exon
18_16952 18 62701913 62702419 1.76 0.0095 506 1529 SYT5-2 Exon
18_17305 18 63672206 63673560 0.69 0.0238 1354 1139 NLRP5-3 Exon
25_06288 25 23550537 23551982 -0.66 0.0183 866 723 LOC782286-1 Exon
15_01221 15 18449268 18449610 0.65 0.0144 291 905 KDELC2-7 Intron
15_01222 15 18449268 18449610 0.79 0.0128 291 905 KDELC2-7 Intron
01_10044 1 118475087 118475364 0.99 0.0004 277 834 SELT-5 Intron
03_14948 3 110252770 110254313 0.59 0.0230 493 1370 MAP7D1-17 Intron
11_14277 11 97170314 97170914 -0.77 0.0355 600 382 FAM125B-2 Intron
04_02959 4 31137285 31137718 0.69 0.0184 433 2997 RAPGEF5-19 Intron
19_00766 19 8526575 8526970 0.60 0.0204 167 262 MSI2-5 Intron
19_00767 19 8526575 8526970 0.65 0.0141 167 262 MSI2-5 Intron
27_00593 27 4507450 4507765 0.68 0.0101 315 247 ANGPT2- 1–8 Intron
25_00821 25 1241931 1242218 0.72 0.0020 287 2812 CRAMP1L Promoter
07_09707 7 45298929 45299941 -0.63 0.0174 1012 4231 ATP5D Promoter
22_11951 22 59732686 59733347 1.10 0.0149 420 1492 ISY1 Ppromoter

CpG_L is the length of the island on the genome while CpG- I indicates the number of bases within the fragment which are part of the CpG Island. Numbers preceded by hyphen following the gene name in the “Genes containing DMRs” column indicate the exon or intron number depending whether the DMR is located in exon or intron of the gene. EDMA_ID refers to the identification ID of each EDMA probe. Each ID is preceded by EDMA_MET. Ppromoter = proximal promoter.