Table 5. Differentially methylated CpG islands at the promoter and proximal promoter regions in IVP blastocyst group.
EDMA_ID | Chromosomal location of DMRs | ||||||||
---|---|---|---|---|---|---|---|---|---|
Chr. No | Start of the fragment | End of the fragment | Log2 FC | P value | CpG-I | CpG_L | Genes containing DMRs | Genomic region of DMRs | |
29_00040 | 29 | 645376 | 646080 | 0.84 | 0.0003 | 363 | 1200 | PANX1 | Ppromoter |
29_04685 | 29 | 37141651 | 37143104 | 0.71 | 0.0127 | 310 | 1924 | ADAMTS15 | ppromoter |
29_02699 | 29 | 25474801 | 25475647 | 0.64 | 0.0002 | 846 | 1918 | NAV2 | Ppromoter |
05_13915 | 5 | 109960314 | 109960564 | -0.63 | 0.0253 | 250 | 533 | GGA1 | Ppromoter |
05_07794 | 5 | 67040732 | 67041118 | -0.63 | 0.0035 | 177 | 237 | PAH | Ppromoter |
25_06093 | 25 | 22177033 | 22177350 | -0.65 | 0.0021 | 260 | 584 | CACNG3 | Ppromoter |
09_02104 | 9 | 28828997 | 28829168 | -0.69 | 0.0071 | 171 | 910 | SMPDL3A | Ppromoter |
12_06617 | 12 | 62665617 | 62665887 | -0.80 | 0.0000 | 178 | 336 | SLITRK5 | Ppromoter |
29_06339 | 29 | 44062208 | 44063331 | -0.84 | 0.0002 | 860 | 975 | CAPN1 | Ppromoter |
09_03387 | 9 | 41554357 | 41555369 | -0.86 | 0.0035 | 1012 | 832 | LOC519522 | Ppromoter |
04_01262 | 4 | 10724605 | 10726568 | -0.93 | 0.0005 | 302 | 286 | CALCR | Ppromoter |
16_12980 | 16 | 78787478 | 78788408 | -0.98 | 0.0011 | 930 | 10103 | LHX9 | Ppromoter |
02_17477 | 2 | 136185489 | 136187433 | -1.04 | 0.0001 | 1143 | 879 | MFAP2 | Ppromoter |
27_04888 | 27 | 37017432 | 7017742 | -1.30 | 0.0000 | 135 | 218 | SLC20A2 | Ppromoter |
17_12743 | 17 | 74699937 | 74701040 | 0.94 | 0.0002 | 353 | 1049 | HIRA | Promoter |
07_09681 | 7 | 45249958 | 45251190 | 0.84 | 0.0011 | 1172 | 1050 | SBNO2 | Promoter |
18_03189 | 18 | 11124182 | 11124888 | 0.78 | 0.0224 | 512 | 353 | ZDHHC7 | Promoter |
02_15404 | 2 | 132517660 | 132518606 | 0.73 | 0.0053 | 946 | 880 | SH2D5 | Promoter |
25_01092 | 25 | 1698431 | 1700218 | 0.71 | 0.0001 | 275 | 275 | TRAF7 | Promoter |
18_13165 | 18 | 52565414 | 52566378 | 0.64 | 0.0091 | 551 | 337 | ZNF235 | Promoter |
13_07039 | 13 | 47917515 | 47918741 | 0.61 | 0.0210 | 1117 | 1102 | PROKR2 | Promoter |
25_00091 | 25 | 209893 | 211620 | -0.62 | 0.0000 | 969 | 898 | HBA, HBQ1 | Promoter |
21_02630 | 21 | 19980747 | 19981499 | -0.63 | 0.0011 | 312 | 1488 | MIR1179, MIR7 | Promoter |
29_05558 | 29 | 41934496 | 41934798 | -0.85 | 0.0269 | 302 | 1146 | CHRM1 | Promoter |
11_16905 | 11 | 103077174 | 103077814 | -0.88 | 0.0072 | 548 | 374 | GTF3C5 | Promoter |
25_06124 | 25: | 22457928 | 22458280 | -1.19 | 0.0002 | 352 | 1146 | RBBP6 | Promoter |
14_01401 | 14 | 4125691 | 4126327 | -1.64 | 0.0001 | 459 | 294 | EIF2C2 | Promoter |
03_01492 | 3 | 12257587 | 12258492 | -2.04 | 0.0000 | 522 | 276 | LOC781123 | Promoter |
CpG_L is the length of the island on the genome while CpG- I indicates the number of bases within the fragment which are part of the CpG Islands. EDMA_ID refers to the identification ID of each EDMA probe. Each ID is preceded by EDMA_MET. Ppromoter = proximal promoter.