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. 2015 Nov 4;10(11):e0141872. doi: 10.1371/journal.pone.0141872

Table 2. Geometric mean MICs (range) of fluconazole products against 6 Candida strains.

Candida strain Fluconazole products P-value (KW)
Pfizer (innovator) Claris Fresenius Vitalis
C. albicans ATCC 90028 0.59 (0.50–1.00) 0.71 (0.50–1.00) 0.71 (0.50–1.00) 0.63 (0.25–1.00) 0.94
C. albicans GRP-0144 0.25 (0.25–0.25) 0.25 (0.25–0.25) 0.25 (0.25–0.25) 0.25 (0.25–0.25) 1.00
C. albicans CIB-19177 5.66 (4.00–8.00) 5.66 (4.00–8.00) 8.00 (4.00–16.0) 6.73 (4.00–16.0) 0.85
C. albicans GRP-0143 0.42 (0.25–0.50) 0.35 (0.25–0.50) 0.30 (0.25–0.50) 0.30 (0.25–0.50) 0.70
C. parapsilosis GRP-0148 1.00 (1.00–1.00) 1.00 (1.00–1.00) 1.00 (1.00–1.00) 1.00 (1.00–1.00) 1.00
C. glabrata GRP-0145 16.0 (16.0–16.0) 19.0 (16.0–32.0) 26.9 (16.0–64.0) 16.0 (16.0–16.0) 0.99

MIC, minimal inhibitory concentration; KW, Kruskal-Wallis test. All assays performed by duplicate, at least twice.