Table 2. Geometric mean MICs (range) of fluconazole products against 6 Candida strains.
Candida strain | Fluconazole products | P-value (KW) | |||
---|---|---|---|---|---|
Pfizer (innovator) | Claris | Fresenius | Vitalis | ||
C. albicans ATCC 90028 | 0.59 (0.50–1.00) | 0.71 (0.50–1.00) | 0.71 (0.50–1.00) | 0.63 (0.25–1.00) | 0.94 |
C. albicans GRP-0144 | 0.25 (0.25–0.25) | 0.25 (0.25–0.25) | 0.25 (0.25–0.25) | 0.25 (0.25–0.25) | 1.00 |
C. albicans CIB-19177 | 5.66 (4.00–8.00) | 5.66 (4.00–8.00) | 8.00 (4.00–16.0) | 6.73 (4.00–16.0) | 0.85 |
C. albicans GRP-0143 | 0.42 (0.25–0.50) | 0.35 (0.25–0.50) | 0.30 (0.25–0.50) | 0.30 (0.25–0.50) | 0.70 |
C. parapsilosis GRP-0148 | 1.00 (1.00–1.00) | 1.00 (1.00–1.00) | 1.00 (1.00–1.00) | 1.00 (1.00–1.00) | 1.00 |
C. glabrata GRP-0145 | 16.0 (16.0–16.0) | 19.0 (16.0–32.0) | 26.9 (16.0–64.0) | 16.0 (16.0–16.0) | 0.99 |
MIC, minimal inhibitory concentration; KW, Kruskal-Wallis test. All assays performed by duplicate, at least twice.