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. Author manuscript; available in PMC: 2016 Aug 15.
Published in final edited form as: Bioorg Med Chem Lett. 2015 May 11;25(16):3382–3389. doi: 10.1016/j.bmcl.2015.04.103

Figure 3.

Figure 3

Design of TX1-85-1 by structure-guided hybridization between 1d and KIN001-111. TX1-85-1 is composed of the covalent bond forming moiety of 1d (square) and the solubilizing tail of KIN001-111 (oval).