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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Cancer Prev Res (Phila). 2015 Aug 31;8(11):1076–1083. doi: 10.1158/1940-6207.CAPR-15-0147

Fig. 2.

Fig. 2

Carcinogen effects on DNA adduct level, cell proliferation, p27Kip1, differentiation and apoptosis over time. A: DNA adduct levels were increased 12 h post-AOM injection and decreased by 48 h after AOM injection (P < 0.001). B: Cell proliferation decreased 12 h after AOM injection and increased at 48 h post-AOM injection (P < 0.001). C: Carcinogen injection did not affect p27Kip1 level. D: Differentiation increased 24 h after AOM injection (P = 0.014). E: Maximum apoptosis was achieved at 24 h post AOM injection (P < 0.001). Data are presented as means ± SE. Means without a common letter are significantly different.