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. Author manuscript; available in PMC: 2016 Dec 3.
Published in final edited form as: Neuroscience. 2015 Sep 2;310:549–560. doi: 10.1016/j.neuroscience.2015.08.068

Figure 1.

Figure 1

Representative examples of calcium activity from barrel cortex neurons in Non-tg, WT α-syn, E57K α-syn, APP, and 3RTau Tg mice. A. Composite two photon image of the calcium indicator dye, OGB (green), and astrocyte marker, SR101 (yellow-orange). B. Respective two photon images indicating the SR101-positve structures. C. Regions of interest for each image. Neurons are numbered and indicated in green; astrocytes are in red. D. The time course for the calcium signal was extracted based on regions of interest identified in the previous panel for 1 and 3 Hz, respectively. The representative neuron number is indicated to the left of each trace. The arrows indicate the onset of the stimulus. Scale bar for photomicrographs is 10 µm.