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. Author manuscript; available in PMC: 2016 Dec 3.
Published in final edited form as: Neuroscience. 2015 Sep 28;310:401–409. doi: 10.1016/j.neuroscience.2015.09.048

Figure 1.

Figure 1

High and low affinity GABAA currents in human sensory neurons. A. In acutely dissociated neurons, a low affinity transient current predominates. GABA was applied at the time indicated. B. After 24hr or more in culture, a high affinity persistent current was detectable. C. Concentration-response data from 10 neurons were normalized with respect to the amplitude of the current evoked with 1 mM GABA. Pooled data were fitted with a Hill equation to yield an EC50 of 540 nM.