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. Author manuscript; available in PMC: 2016 Dec 3.
Published in final edited form as: Neuroscience. 2015 Sep 28;310:401–409. doi: 10.1016/j.neuroscience.2015.09.048

Figure 2.

Figure 2

The kinetics of low affinity GABA (1 mM) evoked currents in human sensory neurons are slower than those observed in rat sensory neurons. A. The fast component of current inactivation was well fitted with a single exponential equation (gray trace) used to estimate the inactivation time constant. Inset: A single exponential function was also used to determine the time constant of current activation. B. Pooled inactivation time constant (tau) data from 11 human and 9 rat neurons were analyzed with a t-test which confirmed that the difference between groups was significant. C. Pooled activation time constant (tau) data from human and rat neurons was also analyzed with a t-test confirming that activation of GABAA currents in rat sensory neurons was faster than in human sensory neurons. * is p < 0.05 and ** is p < 0.01.