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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Drug Alcohol Depend. 2015 Sep 26;156:213–220. doi: 10.1016/j.drugalcdep.2015.09.013

Figure 1.

Figure 1

Effects of mGlu1 antagonist CPCCOEt (0.5–3 μM) on NeuN immunofluorescence in the rat hippocampus. Data are presented as percent control of the mean +/− the SEM. ** = statistical significance (p <0.05) compared to control hippocampi; # = statistical significance (p <0.05) compared to ethanol hippocampi. N = 12 for control hippocampi; N = 17 for hippocampi exposed to ethanol; N = 13 for hippocampi co-exposed to ethanol and 0.5 μM CPCCOEt; N = 14 for hippocampi co-exposed to ethanol and 1.0 μM CPCCOEt; N = 16 for hippocampi co-exposed to ethanol and 3.0 μM CPCCOEt for each primary cell layer of the hippocampal formation. Representative images depict hippocampi exposed to ethanol-naïve media (control) or ethanol media (50 mM), or hippocampi co-exposed to 3.0 μM CPCCOEt and ethanol (50 mM).