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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Drug Alcohol Depend. 2015 Sep 26;156:213–220. doi: 10.1016/j.drugalcdep.2015.09.013

Table 1.

Effects of noncompetitive mGlu1 antagonist CPCCOEt (0.5–3 μM) alone in ethanol-naïve medium. Data are presented as percent control of the mean +/− the SEM. Bold means indicates statistical significance (p <0.05). N = 12 for control hippocampi; N = 12 for hippocampi exposed to 0.5 μM CPCCOEt; N = 14 for hippocampi exposed to 1.0 μM CPCCOEt; N = 14 for hippocampi exposed to 3.0 μM CPCCOEt for each primary cell layer of the hippocampal formation.

NeuN Immunofluorescence CA1 ± SEM CA3 ± SEM DG ± SEM
Control hippocampi 100.00 ± 8.54 100.00 ± 6.14 100.00 ± 5.23
CPCCOEt (0.5 μM) 79.81 ± 9.55 74.26 ± 6.86 82.62 ± 5.95
CPCCOEt (1.0 μM) 64.23 ± 7.79 53.53 ± 5.60 58.35 ± 4.86
CPCCOEt (3.0 μM) 98.69 ± 8.54 80.04 ± 6.14 82.99 ± 5.32