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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Drug Alcohol Depend. 2015 Aug 25;156:29–37. doi: 10.1016/j.drugalcdep.2015.08.013

Table 2.

Sensitivity analysis of analytic methods.

Results Study Sample
Intent to Treat N=175 Modified Intent to Treat N=157 Available Data N=143 Completers N=88
Statistics
OR (95% CI) 1.09 (0.45-2.61) 1.06 (0.44-2.54) 1.11 (0.46-2.65) 1.66 (0.59-4.64)
χ21 0.03 0.01 0.05 0.94
P Value 0.855 0.903 0.823 0.333
% Neg UDS
Busprirone 7.2% (76/1056) 7.9% (76/960) 12.2% (76/622) 13.2% (70/530)
Placebo 6.4% (67/1044) 7.3% (67/924) 11.0% (67/607) 9.9% (49/494)

Intent to treat analysis: Analysis of all randomized participants. Modified intent to treat analysis: Analysis of ITT sample including only those that received study medication. Available data analysis: Analysis using only available, non-missing data. Completer analysis: Analysis of available data on participants who completed the week 12 study visit. Statistical results are shown from the design adjusted models.