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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Drug Alcohol Depend. 2015 Aug 25;156:29–37. doi: 10.1016/j.drugalcdep.2015.08.013

Table 3.

Analysis of the 5-HT1A receptor genotype for the C(-1019)G polymorphism and negative UCT during study treatment; stratified by randomized treatment assignment.

Results Study Sample
Intent to Treat N=172 Completers N=87
Placebo Buspirone Placebo Buspirone
Statistics
OR (95% CI) 1.05 (0.26-4.32) 0.81 (0.24-2.73) 1.45 (0.33-6.37) 0.92 (0.23-3.63)
χ21 0.01 0.11 0.24 0.01
P Value 0.942 0.737 0.625 0.907
% Neg UDS
C/G 6.3% (35/552) 6.4% (30/468) 11.6% (31/268) 11.5% (26/226)
C/C G/G 5.8% (28/480) 8.2% (46/564) 8.00% (18/226) 15.1% (44/292)

Intent to treat analysis: Analysis of all randomized participants. Completer analysis: Analysis of available data on participants who completed the week 12 study visit. Statistical results are shown from the design adjusted models.