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. Author manuscript; available in PMC: 2016 Dec 3.
Published in final edited form as: Neuroscience. 2015 Sep 14;310:322–341. doi: 10.1016/j.neuroscience.2015.09.006

Table 1.

Measures and comparisons of wheel running activity

Measure Computation

Severity of ABA (SOA) in 1st ABA Average of wheel running activity (WRA) during food restriction period (three days of 1st ABA) minus WRA in 1st baseline period

Severity of ABA (SOA) in 2nd ABA Average of wheel running activity (WRA) during food restriction period (2nd, 3rd and 4th days of 2nd ABA) minus WRA in 2nd baseline period

Vulnerability to ABA WRA during period preceding food restriction

Change in vulnerability WRA in 2nd baseline minus WRA in 1st baseline
    ➢ Resistant : value of measure is negative
    ➢ Vulnerable : value of measure is positive

Change in SOA WRA in (2nd ABA minus 2nd baseline) minus (1st ABA minus 1st baseline)
    ➢ Non sensitized : value of measure is negative
    ➢ Sensitized : value of measure is positive

Comparison of WRA in 2ndABA Use

With SOA 1st ABA Response to a repeated stressor

With WRA in 2nd baseline Effect of food restriction in late adolescence

With WRA of first day of 2nd ABA Effect of P4 injection as no injection is given on first day