Table 4.
Spine | Shaft | |||||||
---|---|---|---|---|---|---|---|---|
ANOVA | Effect | Membrane | Cytoplasm | Total | Membrane | Cytoplasm | Total | |
Drug × change in vulnerability | Drug | F | 0.443 | 0.280 | 1.477 | 0.117 | 0.000 | 0.005 |
p | 0.514 | 0.603 | 0.240 | 0.737 | 0.998 | 0.942 | ||
Change in vulnerability | F | 11.139 | 6.511 | 4.862 | 12.211 | 9.515 | 10.209 | |
p | 0.004 | 0.020 | 0.041 | 0.003 | 0.006 | 0.005 | ||
Drug × change in | F | 3.579 | 8.271 | 2.735 | 5.287 | 10.897 | 11.263 | |
p | 0.075 | 0.010 | 0.116 | 0.034 | 0.004 | 0.004 | ||
Drug × change in SOA | Drug | F | 0.742 | 2.965 | 0.122 | 1.362 | 1.238 | 1.106 |
p | 0.400 | 0.102 | 0.731 | 0.258 | 0.280 | 0.307 | ||
Change in SOA | F | 9.853 | 4.165 | 3.855 | 9.582 | 17.830 | 17.852 | |
p | 0.006 | 0.056 | 0.065 | 0.006 | 0.001 | 0.001 | ||
Drug × change in | F | 14.180 | 13.137 | 11.379 | 4.136 | 12.640 | 12.668 | |
p | 0.001 | 0.002 | 0.003 | 0.057 | 0.002 | 0.002 |
The two factors used in the two-way ANOVAs are drug and either change in vulnerability or change in SOA. The significant effects are bolded and in red (dark gray). The marginally significant effects are bolded and italicized. Note that Levene's test for homogeniety of variance was significant (p = 0.02) for the ANOVA on α4-immunoreactivity in the cytoplasm of dendritic shafts despite a square root transformation.