Table 2.
The main statistical parameters of thyroid peroxidase autoantibodies, in males and females, measured by the five automated immunoassay methods
| Sex | No. | Mean (CI 95 %) | SD | CV | Median | p | eURL | mURL | Δ |
|---|---|---|---|---|---|---|---|---|---|
| IMM | |||||||||
| Males | 120 | 8.2 (7.1–9.3) | 6.0 | 73.6 | 6.4 | 0.8 | 28.7 | 35.0 | 18.0 |
| Females | 120 | 8.9 (7.6–10.1) | 7.0 | 79.6 | 6.7 | 29.0 | 17.1 | ||
| MAG | |||||||||
| Males | 120 | 5.5 (4.3–6.6) | 6.5 | 119.8 | 2.7 | 0.8 | 24.6 | 30.0 | 18.0 |
| Females | 120 | 4.9 (3.8–6.1) | 6.2 | 126.3 | 2.2 | 25.4 | 15.3 | ||
| KRY | |||||||||
| Males | 120 | 2.7 (2.5–2.9) | 1.4 | 50.6 | 2.6 | 0.6 | 6.4 | 10.5 | 39.0 |
| Females | 120 | 2.6 (2.3–2.8) | 1.2 | 48.6 | 2.4 | 6.9 | 34.3 | ||
| PHA | |||||||||
| Males | 120 | 2.8 (2.6–3.1) | 1.4 | 50.9 | 2.6 | <0.05 | 8.3 | 25.0 | 66.8 |
| Females | 120 | 3.7 (3.1–3.8) | 1.8 | 51.8 | 3.1 | 10.0 | 60.0 | ||
| LIA | |||||||||
| Males | 120 | 3.2 (2.6–3.9) | 3.4 | 106.0 | 1.9 | 0.8 | 14.2 | 16.0 | 11.3 |
| Females | 120 | 3.2 (2.6–3.9) | 3.9 | 111.3 | 1.7 | 17.9 | 11.9 | ||
CV and Δ are expressed in percentage; Mean, Median, SD, eURL and mURL are expressed in IU/mL. eURL = 99.0th ‰; Δ = ∣mURL − eURL∣/mURL × 100
CI confidence intervals, CV coefficient of variation, eURL experimental upper reference limit, IMM Immulite 2000 XPi, KRY Kryptor Compact Plus, LIA Liaison XL, MAG Maglumi 2000 Plus, mURL manufacturer’s upper reference limit, PHA Phadia 250, SD standard deviation