Figure 4.

Sagittal and axial PET images using [¹⁸F]florbetaben. Both patients are female, are of the same age, and have the same MMSE score. The difference is that the patient on the left has mild cognitive impairment and demonstrates little retention of [¹⁸F]florbetaben, while the patient on the right has Alzheimer's disease and demonstrates high cortical [¹⁸F]florbetaben retention. This retention is represented in the standard pattern seen in AD: highest levels are retained in the posterior cingulate region as well as the frontal and temporal cortices ([59], reprinted with permission).