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. 2015 Nov 5;9:610. doi: 10.3389/fnhum.2015.00610

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Copyright © 2015 Berthier, Dávila, Moreno-Torres, Beltrán-Corbellini, Santana-Moreno, Roé-Vellvé, Thurnhofer-Hemsi, Torres-Prioris, Massone and Ruiz-Cruces.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Axial slices from T₁-weighted MRI images in Montreal Neurological Institute space showing lesion overlap in three patients with loss of regional accent (A). The average lesion density shows involvement of pericentral areas which are considered key components of the large-scale network mediating speech production. The color bar below (A) indicates the number of patients contributing to the average lesion image in both groups. (B) Shows the greatest area of lesion overlap in all three patients involving the medial part of the left precentral gyrus (red). (C) Depicts the areas of lesion overlap superimposed on the Automatic Anatomical Labeling (AAL) atlas (Tzourio-Mazoyer et al., 2002). L: indicates left.