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. 2015 Nov 5;5:16077. doi: 10.1038/srep16077

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(A) Selinexor treatment results in complete cure of HMLE-Snail xenograft. Mice (n = 6 per group) harboring bilateral tumors were exposed to either vehicle or selinexor at 15 mg/kg orally every other day for three weeks. Left panel showing control mice with tumors and right panel showing selinexor treated mice that are completely devoid of tumors (tumor free at 120 days). (B) Mice body weight analysis. *indicates the time point when treatment was stopped and control mice were sacrificed (control tumors reached beyond 2000 mg).