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. 2015 Nov 5;5:16163. doi: 10.1038/srep16163

Figure 1. Histopathological changes of liver sections, miRNA microarray data and validation of differentially expressed miRNAs in mice.

Figure 1

(A) Histopathological changes of liver sections in mice fed MCD diet and control. Hematoxylin and eosin stained (up) and Masson trichromatism stained (down). (B) Effect of MCD diet on serum ALT and AST levels. (C) Differentially regulated miRNAs as identified by miRNA microarray. (D) Validation of microarray data using real-time RT-PCR. Triplicate assays were done for each RNA sample and the relative amount of each miRNA was normalized to U6 snRNA. Values are mean ± SD, **P < 0.01 compared with control.