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. Author manuscript; available in PMC: 2016 Nov 15.

Published in final edited form as: J Neuroimmunol. 2015 Sep 4;288:25–33. doi: 10.1016/j.jneuroim.2015.08.020

Table 1.

Clinical and Demographic Characteristics of Participants (n = 73)

	HIV-Uninfected		HIV-Infected
	n = 44	P-value^* (HIV− vs. HIV+)	Normal	HAND (HIV-associated neurocognitive disorders)		P-value^** (Comparing 3 groups within HIV+)

			n = 17	n = 6 ANI = 6	n = 6 MND = 1 HAD = 5
Gender (% male)	45.5%	p = 0.48	64.7%	50.0%	33.3%	p = 0.46
Age (years)	35.1 (32.2, 38.2)	p = 0.10	33.2 (28.9, 36.5)	33.8 (26.4, 39.6)	33.3 (29.3, 37.1)	p = 0.97
Education (years)	-	-	11 (9, 15)	14 (12, 19)	6 (2, 14)	p = 0.11
NPZ global score	-	-	0.277 (0.086, 0.569)	−0.280 (−0.451, 0.026)	−1.562 (−1.620, −1.466)	p = 0.0002
Log₁₀ Plasma Viral Load (copies/ml)	-	-	4.998 (4.350, 5.469)	4.914 (4.405, 5.161)	5.565 (4.760, 5.589)	p = 0.33
Log₁₀CD14⁺ Total HIV DNA	-	-	1.342 (1.255, 1.568)	1.831 (1.663, 2.199)	2.090 (2.025, 2.152)	p = 0.016
CD4 count (cells/μL)	-	-	239 (159, 328)	331 (261, 397)	190 (30, 310)	p = 0.14
CD8 T cell activation (%)	9.1 (6.8, 12.2)	p < 0.0001	35.9 (31.5, 42.3)	44.7 (38.9, 48.5)	36.8 (35.2, 53.5)	p = 0.60

Data are shown as median (interquartile range), except for gender.

^*

P-values calculated by Fisher's exact test or Wilcoxon-Mann-Whitney test

^**

P-values calculated by Kruskal-Wallis tests