Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Oct 13;6:8506. doi: 10.1038/ncomms9506

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) Confocal image shows ChR2/YEFP fusion protein is highly expressed in sarcolemma (left panel, scale 20 μm) and lightly expressed in honeycomb structures within individual myofibres (middle panel). Illustration (right panel) shows key anatomical structures associated with myofibres including the sarcolemma, myofibrils and T-tubules. (b) Confocal image of a Sim1-Ai32 muscle fibre longitudinal section labelled with DiI (top panel) or DHP calcium channels (bottom panel) to show all membrane-associated structures including T-tubules. DiI and DHP calcium channel staining both co-localize with the EYFP/ChR2 fusion protein, indicating that ChR2 is expressed in the sarcolemma and T-tubule network. Scale bars, 5 μm (a) and 10 μm (b).