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. 2015 Feb 9;34(42):5395–5405. doi: 10.1038/onc.2014.468

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Copyright © 2015 Macmillan Publishers Limited

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Reduced HACE1 expression in breast cancer data sets. (a) mRNA expression analysis for human HACE1 on normal breast and HER2+ invasive ductal breast carcinoma in TCGA breast data set graphed as log2 median-centered ratio. (b) mRNA expression analysis for human HACE1 on normal breast and invasive ductal breast carcinoma in TCGA breast data set graphed as log2 median-centered ratio. (c) HACE1 DNA copy number for blood, normal breast and invasive ductal breast carcinoma in TCGA breast data set graphed as log2 copy number units. Statistical analyses between normal breast and invasive ductal breast carcinoma were conducted using a Student's t-test between groups.