Table 1.
Analysis of Baseline Characteristics of Subjects Stratified by Hemoglobin Type
| Hb SC (n = 3) | Hb CC (n = 2) | Hb AA (n = 242) | Hb AC (n = 39) | Hb AS (n = 14) | |
|---|---|---|---|---|---|
| Number male (%) | 1 (33.3) | 1 (50.0) | 113 (46.7) | 20 (51.2) | 6 (42.9) |
| Mean age at enrollment ± SD (months) | 44.3 ± 31.5 | 51.7 ± 21.7 | 43.8 ± 21.6 | 44.6 ± 22.2 | 48.7 ± 25.9 |
| G6PD A- | 0 | 0 | 26 (10.7%) | 4 (10.3%) | 5 (35.7%) |
| α-thalassemiaa | |||||
| Wild-type (αα/αα) | 1 (50%) | 1 (50%) | 134 (72.8%) | 19 (61.3%) | 7 (63.6%) |
| Heterozygous (−α/αα) | 1 (50%) | 46 (25%) | 12 (38.7%) | 3 (27.3%) | |
| Homozygous (−α/−α) | 1 (50%) | 4 (2.2%) | 0 | 1 (9.1%) | |
| Ethnicity | |||||
| Dogon | 1 (33.3%) | 2 (100.0%) | 182 (75.2%) | 33 (84.6%) | 8 (57.1%) |
| Non-Dogon | 2 (66.7%) | 0 | 60 (24.8%) | 6 (15.4%) | 6 (42.9%) |
| Dropped out/lost to follow-up | 0 | 0 | 17 | 3 | 1 |
Abbreviations: G6PD, glucose-6-phosphate-dehydrogenase; Hb, hemoglobin.
a α-thalassemia testing consent was obtained for 250 children; of these, samples from 240 achieved results.