Table 2.

Univariate logistic regression analyses for development of acute renal impairment during bouts

Variable	OR for Renal Impairment (95% CI)	P Value
Age at onset (adulthood versus childhood)a	24.6 (1.1 to 542.4)	0.04
No. of episodes per year (<1 versus ≥1)	54.6 (2.3 to 1326.3)	0.01
Sex (F versus M)	15.0 (1.2 to 185.2)	0.03
Neurologic signs (no versus yes)	0.1 (0.007 to 3.21)	0.22
In vitro rADAMTS13 secretion level (>3.75% versus ≤3.75%)	325 (6 to 18339)	0.005
In vitro rADAMTS13 activity level (>0.4% versus ≤0.4%)	91.7 (3.2 to 2623.5)	0.008

95% CI, 95% confidence interval; F, female; M, male; rADAMTS13, recombinant a disintegrin and metalloprotease with thrombospondin motifs 13.

^aChildhood <18 years; adulthood ≥18 years.