Table 1.
Variable (Visit 4 Unless Specified) | History of Stones (n=856) | No History of Stones (n=9822) | P Value |
---|---|---|---|
Age (yr) | 63.1±5.7 | 62.5±5.6 | 0.002 |
Men | 66.1 | 42 | <0.001 |
African-American race | 9.7 | 22.8 | <0.001 |
Body mass index (kg/m2) | 28.7±5.2 | 28.8±5.7 | 0.63 |
BP (mmHg) | |||
Systolic | 127.2±18.1 | 127.2±18.8 | 0.95 |
Diastolic | 70.9±9.9 | 71.1±10.3 | 0.72 |
Hypertension | 46.8 | 45.6 | 0.56 |
Use of antihypertensive medications | 44.7 | 41.4 | 0.06 |
Diabetes | 19.5 | 15.7 | 0.003 |
History of coronary artery disease | 11.3 | 7.5 | <0.001 |
Cholesterol (mg/dl) | |||
Total | 195.1±33.3 | 200.7±37.0 | <0.001 |
HDL | 45.8±14.9 | 50.5±16.5 | <0.001 |
LDL | 119.9±30.8 | 122.4±33.4 | 0.04 |
Triglycerides (mg/dl) | 130.9 (94.9, 180.8) | 120.9 (86.9, 170.8) | <0.001 |
Use of lipid-lowering medications | 18.1 | 13.5 | <0.001 |
Plasma uric acid (mg/dl) | 5.7±1.4 | 5.5±1.5 | 0.001 |
History of gout | 7.8 | 5.2 | 0.001 |
Allopurinol use | 2.6 | 1.2 | <0.001 |
Diuretic use (%) | 8.9 | 8.7 | 0.89 |
eGFR (ml/min per 1.73 m2) | 87.7±12.4 | 88.7±13.3 | 0.03 |
Smoking status | |||
Current | 13.2 | 15.1 | <0.001 |
Former | 52.0 | 42.4 | |
Alcohol use (%) | |||
Current drinker | 46.3 | 50.1 | 0.006 |
Former drinker | 34.3 | 29.1 | |
High-sensitivity C-reactive protein (mg/L) | 2.1 (0.9, 4.5) | 2.4 (1.1, 5.5) | <0.001 |
Study center (%) | <0.001 | ||
Forsyth County, North Carolina | 37.4 | 23.6 | |
Jackson, Mississippi | 7.9 | 20.5 | |
Minneapolis, Minnesota | 21.4 | 29.3 | |
Washington County, Maryland | 33.3 | 26.7 | |
Sports score, visit 3 | 2.6±0.8 | 2.5±0.8 | 0.002 |
Urine albumin-to-creatinine ratio (μg/mg) | 4.0 (1.7, 9.7) | 3.7 (1.8, 7.3) | 0.16 |
Continuous variables are presented as means ± SDs, percentages, or medians (interquartile ranges) unless otherwise indicated.